Uniaxially fixed mechanical boundary condition elicits cellular alignment in collagen matrix with induction of osteogenesis
نویسندگان
چکیده
منابع مشابه
Mechanical induction of Osteogenesis. Preliminary studies.
The animal model developed in the Soviet Union by Ilizarov has been reliably reproduced by us for the mechanical induction of osteogenesis using slow distraction. Our preliminary studies in six adult dogs indicate that this osteogenesis originates from well-structured intramembranous ossification, with rapid maturation to lamellar bone, indistinguishable from surrounding host bone. Mineralizati...
متن کاملdeterminant of the hankel matrix with binomial entries
abstract in this thesis at first we comput the determinant of hankel matrix with enteries a_k (x)=?_(m=0)^k??((2k+2-m)¦(k-m)) x^m ? by using a new operator, ? and by writing and solving differential equation of order two at points x=2 and x=-2 . also we show that this determinant under k-binomial transformation is invariant.
15 صفحه اولMineralized collagen scaffolds induce hMSC osteogenesis and matrix remodeling.
Biomaterials for bone tissue engineering must be able to instruct cell behavior in the presence of the complex biophysical and biomolecular environments encountered in vivo. While soluble supplementation strategies have been identified to enhance osteogenesis, they are subject to significant diffusive loss in vivo or the need for frequent re-addition in vitro. This investigation therefore explo...
متن کاملInfluence of cyclic mechanical stretch and tissue constraints on cellular and collagen alignment in fibroblast-derived cell sheets.
Mechanical forces play an important role in shaping the organization of the extracellular matrix (ECM) in developing and mature tissues. The resulting organization gives the tissue its unique functional properties. Understanding how mechanical forces influence the alignment of the ECM is important in tissue engineering, where recapitulating the alignment of the native tissue is essential for ap...
متن کاملNvestigation of a Boundary Layer Problem for Perturbed Cauchy-Riemann Equation with Non-local Boundary Condition
Boundary layer problems (Singular perturbation problems) more have been applied for ordinary differential equations. While this theory for partial differential equations have many applications in several fields of physics and engineering. Because of complexity of limit and boundary behavior of the solutions of partial differential equations these problems considered less than ordinary case. In ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-88505-z